Theophylline & Salbutamol Tablets 100/2mg

About Theophylline & Salbutamol Tablets 100/2mg

Theophylline & Salbutamol Tablets (100/2 mg) are a combination medication that contains two active ingredients, Theophylline (100 mg) and Salbutamol (2 mg). This combination is primarily used to manage respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Each ingredient plays a distinct role in helping to alleviate symptoms and improve breathing.

Key Details about Theophylline & Salbutamol Tablets 100/2 mg:

Active Ingredients:

• Theophylline (100 mg): A bronchodilator that works by relaxing the muscles around the airways in the lungs, allowing them to open up and make breathing easier. Theophylline also helps in controlling inflammation and increasing the clearance of mucus from the airways.
• Salbutamol (2 mg): A beta-agonist (or bronchodilator) that specifically targets the smooth muscles of the airways, causing them to relax and open up. It helps in relieving bronchospasm and makes it easier to breathe.

Common Uses:

• Asthma: This combination is often prescribed for patients with chronic asthma, where the airways become constricted and inflamed, making it difficult to breathe.
• Chronic Obstructive Pulmonary Disease (COPD): In COPD, the airways in the lungs are partially obstructed, leading to difficulty breathing. The combination of Theophylline and Salbutamol helps manage symptoms by improving airflow and reducing bronchoconstriction.
• Prevention of Bronchospasm: This medication is used to help prevent bronchospasm (tightening of the muscles around the airways) associated with asthma, COPD, or other chronic respiratory conditions.

Mechanism of Action:

• Theophylline: Theophylline works by inhibiting phosphodiesterase enzymes, leading to increased levels of cyclic AMP (cAMP) in the cells. This results in the relaxation of the smooth muscles in the airways, preventing bronchoconstriction. It also has mild anti-inflammatory effects, helping to reduce airway inflammation.
• Salbutamol: Salbutamol works by stimulating beta-2 adrenergic receptors in the smooth muscle cells of the airways. This leads to muscle relaxation and dilation of the airways, which eases the flow of air into the lungs and relieves symptoms like wheezing and shortness of breath.

Dosage:

• Adults: Typically, 1 tablet (100 mg Theophylline and 2 mg Salbutamol) is taken 2 to 3 times daily. The dosage may vary depending on the severity of the symptoms, the patients medical condition, and the doctor's recommendations.
• Children: The use of this combination is usually not recommended in children under a certain age. A doctor will determine if it is safe and appropriate for a child to use this combination based on their medical condition.

Side Effects:

• Common Side Effects:

  • Tremors (shakiness, especially in the hands)
  • Headache
  • Increased heart rate (tachycardia)
  • Nausea or vomiting
  • Insomnia or restlessness
  • Dizziness or lightheadedness

• Serious Side Effects:

  • Palpitations or an irregular heartbeat
  • Chest pain
  • Severe allergic reactions (rash, itching, swelling, especially of the face/tongue/throat)
  • Severe headaches
  • Seizures (rare, but possible with high levels of theophylline)

Precautions:

• Heart Conditions: Theophylline and Salbutamol can cause an increase in heart rate or palpitations, so caution is needed in individuals with heart problems, such as arrhythmias, high blood pressure, or coronary artery disease.
• Liver or Kidney Disease: Patients with liver or kidney dysfunction may require dose adjustments, as these organs are involved in metabolizing the drug.
• Seizure Risk: Theophylline may increase the risk of seizures, particularly in individuals with a history of seizure disorders.
• Pregnancy and Breastfeeding: Always consult a healthcare provider before taking this medication during pregnancy or breastfeeding. While it is often used during pregnancy, it should only be used when the benefits outweigh the risks.
• Caffeine and Other Stimulants: Patients should avoid excessive intake of caffeine or other stimulants while using Theophylline, as they can increase the likelihood of side effects like tremors or tachycardia.

Interactions:

• Other Medications: This combination can interact with other medications, including other bronchodilators, antibiotics, antifungals, and antidepressants. For example, Cimetidine, Erythromycin, and Fluoroquinolone antibiotics can increase the blood levels of Theophylline, leading to a higher risk of side effects.
• Corticosteroids: When taken together with corticosteroids, these medications can sometimes reduce inflammation more effectively, but close monitoring is required.
• Antihypertensives: Salbutamol may counteract the effects of certain blood pressure-lowering medications, so monitoring blood pressure is important.

Storage:

• Store the tablets in a cool, dry place away from heat and moisture.
• Keep the medication in its original packaging to protect it from light.
• Ensure the medication is kept out of the reach of children.

Conclusion:

Theophylline & Salbutamol Tablets 100/2 mg are used to treat chronic respiratory conditions like asthma and COPD by helping to relax the muscles around the airways and improve airflow. The combination of Theophylline and Salbutamol works together to reduce bronchospasm and inflammation, making it easier to breathe.

Advanced Bronchodilator Combination

Theophylline & Salbutamol Tablets 100/2mg leverage the synergistic action of two active bronchodilators, providing effective relief from asthma and COPD. The combination addresses both airway inflammation and constriction, delivering targeted therapy to improve breathing and reduce respiratory distress.


Easy Oral Administration and Convenient Packaging

These pharmaceutical tablets are designed for oral use and come in blister strips, ensuring every dose is protected from environmental exposure. The tablets are portable, making adherence to prescribed treatment regimens simple whether at home or on the move.


Assured Quality and Shelf Stability

Produced to stringent pharmaceutical standards, Theophylline & Salbutamol Tablets offer high accuracy in dosage and quality. With a shelf life of 24 months and storage recommendations below 25C, the product remains effective and stable over extended periods.