Perfecine Pirfenidone Tablets IP 200mg

About Perfecine Pirfenidone Tablets IP 200mg

Perfecine Pirfenidone Tablets IP 200 mg is a medication used to treat idiopathic pulmonary fibrosis (IPF), a progressive lung disease that causes scarring of the lung tissue, leading to difficulty breathing. Pirfenidone is the active ingredient, and it works by reducing the production of certain proteins that contribute to the scarring process in the lungs. It is classified as an anti-fibrotic agent.

How it works:

Pirfenidone helps to slow down the progression of pulmonary fibrosis by reducing the activity of certain inflammatory and fibrotic pathways in the body. It also has antioxidant and anti-inflammatory effects, which can help in managing the symptoms of lung scarring and improve lung function.

Common uses:

• Idiopathic pulmonary fibrosis (IPF): Pirfenidone is primarily used for the treatment of IPF to slow the decline in lung function, improve quality of life, and reduce the risk of complications associated with the condition.

Dosage and administration:

• The typical starting dose is 200 mg, which may be gradually increased depending on the patient's tolerance and as prescribed by a doctor.
• Initially, the dosage is often 200 mg three times a day (600 mg/day), and it may be increased to 400 mg three times a day (1200 mg/day) over time.
• It is recommended to take the tablets with food to minimize stomach irritation.

Possible side effects:

• Gastrointestinal issues: Nausea, diarrhea, or loss of appetite are common, especially at the beginning of treatment.
• Fatigue: Some people may experience tiredness or weakness.
• Liver problems: Pirfenidone may affect liver function, so regular monitoring of liver enzymes is required.
• Skin reactions: Rash, redness, or sensitivity to sunlight (photosensitivity) can occur, so it's important to avoid prolonged sun exposure.

Warnings and precautions:

• Liver function monitoring: Because pirfenidone can affect liver function, liver enzymes should be regularly checked during treatment.
• Photosensitivity: Patients using pirfenidone should avoid direct sunlight, wear protective clothing, and use sunscreen to prevent sunburn.
• Pregnancy and breastfeeding: Pirfenidone should not be used during pregnancy unless absolutely necessary. It's also not recommended during breastfeeding.

Important considerations:

• Drug interactions: Always inform your doctor about other medications you are taking, as pirfenidone can interact with certain drugs.
• Adherence to the prescribed regimen: It's crucial to follow your healthcare provider's instructions carefully, as pirfenidone is most effective when taken consistently.