Paznib Pazopanib Tablets 400mg

About Paznib Pazopanib Tablets 400mg

Paznib (Pazopanib) Tablets 400 mg contain pazopanib, a targeted therapy medication used primarily for the treatment of certain types of cancer. Pazopanib is an oral tyrosine kinase inhibitor that works by blocking multiple receptor tyrosine kinases involved in the growth and spread of cancer cells. By inhibiting these pathways, pazopanib helps slow down the growth of tumors and the development of blood vessels that supply the tumor (angiogenesis).

Common uses of Paznib (Pazopanib):

1. Renal cell carcinoma (RCC): Pazopanib is commonly used to treat advanced kidney cancer (renal cell carcinoma), especially when surgery or other treatments have not been effective.
2. Soft tissue sarcoma (STS): Pazopanib is also used for the treatment of advanced or metastatic soft tissue sarcoma, a type of cancer that affects the connective tissues, including muscles, fat, and blood vessels.
3. Other cancers: Although less common, pazopanib may be explored for other cancers in clinical settings depending on the type and stage of cancer.

How it works:

Pazopanib targets and inhibits several tyrosine kinases involved in processes that promote the growth, spread, and blood supply to tumors. It specifically inhibits vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptors (PDGFR), and c-kit receptors, which are involved in the growth and survival of cancer cells and the formation of blood vessels that support tumor growth.

Common side effects of Paznib:

• Diarrhea: This is a frequent side effect of pazopanib.
• Fatigue or tiredness
• High blood pressure (hypertension): Pazopanib can increase blood pressure, so monitoring is important.
• Liver problems: Pazopanib may cause liver enzyme changes, so regular liver function tests are needed.
• Skin rashes or nail changes (such as discoloration or brittleness)
• Loss of appetite or weight loss
• Nausea and vomiting
• Hand-foot syndrome (redness, swelling, or pain on the palms of hands or soles of feet)
• Mouth sores (stomatitis)

Important considerations:

• Blood pressure monitoring: Since pazopanib can cause high blood pressure, it's essential to have regular blood pressure checks during treatment. If hypertension becomes severe, your doctor may prescribe antihypertensive medications.
• Liver function: Regular blood tests are recommended to monitor liver function, as pazopanib can cause liver toxicity.
• Drug interactions: Pazopanib can interact with other medications, including those that affect liver enzymes, so it's important to inform your doctor about all other medications you're taking.
• Pregnancy and breastfeeding: Pazopanib should not be used during pregnancy due to potential harm to the fetus. It is also not recommended for breastfeeding, as it can pass into breast milk.
• Stopping treatment: If you experience severe side effects like liver issues, your doctor may need to adjust or stop your pazopanib treatment.

Pazopanib can be an effective treatment for certain cancers, but like all cancer therapies, it comes with potential side effects and requires careful monitoring throughout treatment. Be sure to follow your doctor's recommendations and attend regular check-ups to ensure the medication is working effectively and safely.