Artemether & Lumefantrine Tablets Ph. Int. 20/120mg

About Artemether & Lumefantrine Tablets Ph. Int. 20/120mg

Artemether and Lumefantrine are combined in a tablet form to treat malaria, a parasitic infection transmitted by mosquitoes. This combination is commonly used to treat uncomplicated malaria caused by Plasmodium falciparum, one of the most common and severe types of malaria-causing parasites.

Active ingredients:

• Artemether (20mg): A fast-acting antimalarial drug that works by killing the malaria parasite at an early stage in the red blood cells. It is derived from the herb Artemisia annua (sweet wormwood) and has a rapid onset of action.
• Lumefantrine (120mg): A longer-acting antimalarial drug that works by inhibiting the growth of the malaria parasite in the red blood cells. It has a slower onset of action but remains effective for a longer duration.

Common uses:

• Treatment of uncomplicated malaria: Artemether and Lumefantrine are primarily prescribed to treat uncomplicated malaria caused by Plasmodium falciparum.
• Preventing malaria progression: The combination works synergistically to reduce the parasite load in the body, helping to clear the infection more effectively.

Dosage:

• The typical dosage for adults and children is based on body weight and the severity of the malaria infection.
• Standard regimen: The usual treatment involves taking the tablet twice a day (for example, once in the morning and once in the evening) for 3 days. The exact dosing schedule should be followed based on the prescribing healthcare provider™s instructions.
• Dosage adjustment: The specific number of tablets or doses may vary depending on the individual™s weight, so it™s important to follow the prescribed instructions carefully.

Side effects:

• Common side effects: Headache, dizziness, nausea, vomiting, and fatigue.
• Serious side effects (less common): Heart rhythm problems (QT prolongation), allergic reactions, liver damage, and anemia.

Warnings and precautions:

• Heart issues: Artemether and Lumefantrine can affect the heart's rhythm, particularly in individuals with pre-existing heart conditions or those taking other medications that affect the heart. Monitoring for heart rhythm changes is recommended.
• Liver function: Individuals with liver problems may need dosage adjustments or alternative treatments, as the medication is metabolized by the liver.
• Drug interactions: Artemether and Lumefantrine may interact with other medications, especially those that affect the liver or heart. Always inform your healthcare provider about other medications you are taking.
• Pregnancy and breastfeeding: The medication should only be used during pregnancy if the benefit outweighs the risk, and caution is advised when breastfeeding.

Precautions:

• Complete the full course: It is essential to complete the full prescribed course of Artemether and Lumefantrine to ensure the malaria is fully treated and to prevent resistance.
• Monitoring: Regular follow-ups may be necessary to monitor the effectiveness of the treatment and to check for any adverse effects.