Fluconazole Tablets USP 150mg

Product Description

Fluconazole Tablets USP 150mg is an antifungal medication used to treat a variety of fungal infections. It belongs to a class of drugs known as azole antifungals, which work by inhibiting the growth of fungi and yeast.

Key Information about Fluconazole Tablets USP 150mg:

Active Ingredient:

• Fluconazole (150 mg) is the active ingredient. It works by inhibiting an enzyme called lanosterol 14-alpha-demethylase, which is essential for the synthesis of ergosterol, a key component of fungal cell membranes. Without ergosterol, the fungus's cell membrane becomes damaged, leading to the death of the fungus.

Indications (Uses):

Fluconazole is commonly prescribed for:

• Vaginal candidiasis (yeast infections): A single dose of 150mg is often effective for treating vaginal yeast infections caused by Candida species.
• Oral thrush: An infection of the mouth caused by Candida species.
• Esophageal candidiasis: A more severe form of Candida infection affecting the esophagus.
• Fungal infections of the skin: Such as ringworm and athlete's foot.
• Systemic fungal infections: Fluconazole can be used for treating more severe, systemic fungal infections, including cryptococcal meningitis in immunocompromised patients.

Dosage:

• For vaginal candidiasis: Typically, a single dose of 150 mg is recommended.
• For other infections: The dosage may vary depending on the type and severity of the infection. Fluconazole 150 mg may be taken as a single dose or as part of a longer treatment regimen, depending on the doctor™s instructions.

Fluconazole Tablets are generally taken once a day with or without food. It is essential to follow the prescribed dosage and complete the entire course of treatment, even if symptoms improve before the medication is finished.

Side Effects:

Common side effects of fluconazole may include:

• Headache
• Nausea
• Abdominal pain
• Diarrhea
• Skin rash

Serious side effects are rare but may include:

• Liver toxicity: Signs include yellowing of the skin or eyes, dark urine, or severe abdominal pain.
• Severe allergic reactions: Such as swelling of the face or throat, difficulty breathing, or hives.
• Heart problems: Including abnormal heart rhythms (QT prolongation).

Precautions:

• Liver disease: Fluconazole should be used cautiously in patients with liver problems, as it can affect liver function.
• Drug interactions: Fluconazole can interact with other medications, such as warfarin, phenytoin, and oral contraceptives. Inform your healthcare provider of all medications you are taking.
• Pregnancy: Fluconazole is not recommended during pregnancy, especially in high doses. Consult a doctor before use if pregnant or planning to become pregnant.
• Breastfeeding: Fluconazole passes into breast milk, so it should only be used during breastfeeding if the benefits outweigh the risks.

Storage:

• Store at room temperature (15C to 30C or 59F to 86F).
• Keep the tablets in their original packaging and out of direct sunlight.
• Keep out of reach of children.

Conclusion:

Fluconazole Tablets USP 150mg is a highly effective treatment for fungal infections, particularly vaginal yeast infections and other Candida-related infections. It is typically well-tolerated, though some individuals may experience side effects like headache or gastrointestinal discomfort.