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Neukine 300mcg Pfs

Neukine 300mcg Pfs Specification

Instruments Type
Injection, Prefilled Syringe

Function
Increases Neutrophil Count

Measurement Range
Each syringe contains 300 mcg/0.5ml

Features
Ready to Administer, Pre-measured Dose, Sterile, Single-Use

Accuracy
Pharmaceutical Grade Dosage Accuracy

Usage Type
Medical, Hospital, Clinic, Oncology

Storage Instructions
Store at 2C to 8C, Do not freeze, Protect from light

Shelf Life
24 months from manufacturing date

Frequency
As per Physicians Direction

Equipment Type
Prefilled Syringe

Material
Sterile Pharmaceutical Grade with Pre-filled Glass Syringe

Condition
New, Sterile, Ready-to-Use

Technology
Biotechnology Derived Recombinant G-CSF

Portable
Yes

Wall Mounted
No

Operating Type
Parenteral Administration

Use
Promotes Neutrophil Production, Used in Chemotherapy Induced Neutropenia

Color
Transparent Syringe with Colourless Solution

Container Type
Sterile Glass Syringe

Solution Appearance
Clear, Colourless, Aqueous Solution

Route of Administration
Subcutaneous or Intravenous

Brand Name
Neukine

Marketed Form
Pre-filled Syringe with Plunger and Needle Guard

Prescription Required
Yes

Generic Name
Filgrastim

Packing
1 Prefilled Syringe per Pack

Strength
300 mcg

Indication
Neutropenia, Bone Marrow Transplant, Myelosuppressive Therapy

Neukine 300mcg Pfs Trade Information

Minimum Order Quantity
100 Packs

FOB Port
AHMEDABAD

Payment Terms
Paypal, Cash Advance (CA), Cash in Advance (CID), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C)

Delivery Time
3 Days

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
Box

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Main Domestic Market
All India

About Neukine 300mcg Pfs

Neukine 300 mcg Vial contains Lenograstim, which is a granulocyte colony-stimulating factor (G-CSF). G-CSF is a type of growth factor that stimulates the production of white blood cells, specifically neutrophils, which are essential for fighting infections.

Key Uses:

Chemotherapy-Induced Neutropenia: Neukine is primarily used to prevent or treat neutropenia (low white blood cell count) that is caused by chemotherapy. Chemotherapy can damage the bone marrow, leading to a decrease in neutrophils and an increased risk of infection. Neukine helps stimulate the bone marrow to produce more neutrophils.
Bone Marrow Disorders: It is also used in patients with bone marrow disorders, such as myelodysplastic syndromes or acute myeloid leukemia (AML), to support the recovery of the bone marrow.
Post-Surgical or Post-Transplant: In certain situations, Neukine may be used after surgery or bone marrow transplants to promote faster recovery of white blood cell counts.

Mechanism of Action:

Lenograstim is a recombinant form of the human granulocyte colony-stimulating factor (G-CSF). It works by binding to specific receptors on the surface of the bone marrow cells, stimulating them to produce and release more neutrophils into the bloodstream. These neutrophils help the body fight bacterial infections and support immune function.

Common Side Effects:

Bone pain: One of the most common side effects, as G-CSF can cause bone marrow stimulation, leading to discomfort or pain in the bones.
Fever or chills.
Headache.
Fatigue.
Nausea.

Serious Side Effects:

Splenic rupture: In rare cases, there can be a risk of splenic rupture (enlargement of the spleen or splenic injury).
Leukocytosis: Overproduction of white blood cells, which can increase the risk of some types of blood disorders.
Allergic reactions: Skin rashes, swelling, or more severe reactions like difficulty breathing.
Respiratory issues: Rarely, patients may experience difficulty breathing or other respiratory problems.

Dosage:

The typical dosage of Neukine 300 mcg Vial depends on the patient's condition and response to treatment. The medication is usually administered as an injection under the skin (subcutaneous) or into the vein (intravenous). The exact dosage and frequency will be determined by a healthcare provider, but it is often given daily or several times a week.

Administration:

Subcutaneous Injection: The 300 mcg vial is reconstituted with the provided diluent and is administered as a subcutaneous injection.
Intravenous Infusion: In certain cases, it may be administered intravenously.

Precautions:

Blood Counts: Close monitoring of blood counts is important during treatment to ensure that the white blood cell count doesn't rise too high.
Bone Marrow Function: Patients with pre-existing bone marrow disorders should be monitored carefully as Neukine stimulates bone marrow.
Allergic Reactions: If signs of an allergic reaction, such as rash, swelling, or difficulty breathing, occur, the treatment should be discontinued, and immediate medical attention is necessary.
Pregnancy and Breastfeeding: The safety of Neukine during pregnancy and breastfeeding has not been established, so it should only be used if absolutely necessary and under strict medical supervision.

Summary:

Neukine 300 mcg Vial is a recombinant G-CSF used to stimulate the production of neutrophils in patients with neutropenia, particularly due to chemotherapy. It helps reduce the risk of infections by increasing white blood cell production. Common side effects include bone pain, fever, and fatigue, while more serious side effects can include splenic rupture and allergic reactions. Regular monitoring of blood counts and bone marrow function is essential.

Biotechnology-Derived Reliability

Neukine utilizes advanced recombinant biotechnology to deliver Filgrastim, a vital medication for patients who need boosted neutrophil counts. Its pharmaceutical precision ensures consistent outcomes, facilitating management of neutropenia in oncology and post-transplant care. Designed with a sterile, prefilled glass syringe, each dose meets rigorous quality standards for safety and efficacy.

Ready-to-Use Convenience

Supplied in a pre-measured, single-use syringe, Neukine simplifies dosing and administration for healthcare professionals. The clear solution and transparent syringe design aid accurate visual inspections. Portable and easy to handle, the syringe is equipped with a needle guard, ensuring user safety and reducing preparation errors during use in hospitals or clinics.

Safe Storage and Handling

Neukine is shelf-stable for up to 24 months when stored between 2C and 8C, away from light and not frozen. Its robust packaging safeguards against contamination while maintaining sterility. Detailed instructions accompany each pack, supporting healthcare providers in correct administration and ensuring optimal patient outcomes.

FAQ's of Neukine 300mcg Pfs:

Q: How should Neukine 300mcg Pfs be administered?

A: Neukine should be administered as an injection, either subcutaneously or intravenously, by a healthcare professional following the physician's directions. The ready-to-use prefilled syringe streamlines the process and ensures accurate dosing.

Q: What are the primary uses and indications for Neukine?

A: Neukine is mainly used to promote neutrophil production in cases of neutropenia, particularly in patients receiving chemotherapy, undergoing bone marrow transplants, or undergoing myelosuppressive therapy. It is effective in increasing neutrophil count and reducing infection risk in these conditions.

Q: When and how often should Neukine be used?

A: The frequency and duration of Neukine administration are determined by the prescribing physician, tailored to individual patient needs and treatment plans. Always follow medical advice regarding timing and dosage.

Q: Where should Neukine be stored before use?

A: Neukine must be stored in a refrigerator at 2C to 8C. It should be protected from light, never frozen, and kept in its original packaging until use to maintain sterility and effectiveness.

Q: What is the benefit of using a prefilled syringe for Neukine?

A: The prefilled syringe offers precise, pre-measured dosing, enhancing accuracy and safety while minimizing preparation time and contamination risk. Its design includes a needle guard for safe handling and single-use administration.

Q: Who should use Neukine and is a prescription required?

A: Neukine is intended for use under medical supervision in hospitals, clinics, or oncology settings. It requires a valid prescription and should only be administered by trained healthcare professionals.

Q: What precautions should be taken during Neukine administration?

A: Healthcare providers should only administer Neukine after visually inspecting the solution to confirm it is clear and colourless. Strict adherence to dosage, storage instructions, and aseptic procedures is essential for patient safety.

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